Zoonotic and antibiotic-resistant Campylobacter: a view through the One Health lens

As a pathogen of a major public health concern with animal health importance, Campylobacter constitutes a clear and present threat to One Health. This organism colonizes the intestinal tract and is widely distributed among various animal species, including livestock and poultry, companion animals, and wildlife. As a result of its broad distribution, Campylobacter is exposed to antibiotics used in both human and veterinary medicine, which creates antibiotic selection pressure that has driven the development and rising prevalence of antibiotic resistant Campylobacter. This is particularly evident with the resistance to fluoroquinolone (FQ), which has become a great concern for public health.