Unmasking MRSA antibiotic resistance: the impact of environment, pollution, and healthcare quality—a nationwide exploration in China: a comprehensive analysis spanning 2014 to 2021 in mainland China

Antibiotic resistance, particularly methicillin-resistant Staphylococcus aureus (MRSA), is a growing global health concern. A study in China found significant positive associations between MRSA AMR and factors like cadmium pollution, soybean and poultry production, oil consumption, tap water coverage, corn and pork production, and antibiotic use intensity. The predictive model explained 52.7% of the variability in MRSA AMR, highlighting the need for integrated strategies to address regional environmental and healthcare quality in combating antibiotic resistance.