Trends and predictors of antimicrobial resistance among patients with urinary tract infections at a tertiary hospital facility in Alexandria, Egypt: a retrospective record-based classification and regression tree analysis

The study aimed to study Antimicrobial Resistance (AMR) patterns and predictors among patients with UTIs admitted to the Urology Department at Alexandria University Hospital. The study involved 469 patients and included demographic data, diagnosis, chronic diseases, hospital stay duration, catheter insertion, antibiotic use history, and urinary tract operations. The most commonly isolated bacterium was Escherichia coli, followed by Klebsiella pneumoniae. Multidrug resistance (MDR) was found in 67.7% of hospital-acquired UTIs and 49.4% of community-acquired UTIs. Risk factors included antibiotic use within three months, hospital-acquired UTI, diabetes mellitus, age over 60 years, and recurrent UTI. The study concluded that assessing resistance patterns in hospitals is crucial for improving antibiotic treatment and preventing further AMR increases.