The genetic relationship between human and pet isolates: a core genome multilocus sequence analysis of multidrug-resistant bacteria

The global increase of multidrug-resistant organisms (MDROs) is a pressing public health threat, affecting both humans and animals. The One Health concept emphasizes the interconnectedness of human, animal, and environmental health. A study using core genome multilocus sequence typing (cgMLST) investigated the genetic relationships and potential transmission of MDROs between humans and pets. The majority of samples were genetically distinct, but some had low allelic differences. Two cases of putative household transmission or shared sources of VR E. faecium and MDR E. coli were documented.