Light-Activable Inhibitor Overcomes Antimicrobial Resistance and Regulates Antibacterial Activity
Overuse and environmental accumulation of antibiotics contribute to antimicrobial resistance, a global health threat. PhoPS, a photocaged β-lactamase inhibitor, has been designed and synthesized. It exhibits rapid photoactivation, stability, and light-activated inhibition. It synergizes with cefoperazone against Escherichia coli strains and can suppress resistance development, suggesting a promising approach.
OUR UNDERWRITERS
Unrestricted financial support by:
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Antimicrobial Resistance Fighter Coalition |
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Bangalore Bioinnovation Centre |
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INTERNATIONAL FEDERATION PHARMACEUTICAL MANUFACTURERS & ASSOCIATIONS |
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BD |
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