Characterization and therapeutic potential of newly isolated bacteriophages targeting the most common Salmonella serovars in Europe

The study identifies five phage isolates as potential candidates for phage therapy in controlling Salmonella in primary production. These phages demonstrated physical stability, effectively lysing 12 Salmonella serovars and multidrug-resistant strains. They also exhibited depolymerase production, suggesting potential as surface-disinfecting agents. The phages belong to distinct genera and have no harmful sequences, making them suitable for phage therapy applications or phage-based Salmonella eradication strategies. Integrating these phages into existing biocontrol measures could improve food safety and public health.