Antimicrobial resistance in plant endophytes associated with poultry-manure application revealed by selective culture and whole genome sequencing

Poultry manure, used as organic fertilizer in agriculture, has been linked to the increase in antimicrobial resistance genes (ARGs) in plant endophytes. Studies have shown that the addition of poultry manure can increase the abundance of genes associated with resistance to various antibiotics. This highlights the need for responsible antibiotic use in poultry and animal farming to reduce contamination and transgression into endophytic plant microbiome compartments. Proper manure management practices and vigilance in monitoring and surveillance efforts are also crucial to tackle antibiotic resistance.