A systematic review and meta-analysis on antibiotic resistance genes in Ghana
A systematic review and meta-analysis of 371 articles on antimicrobial resistance (ARGs) in Ghana revealed that bacteria from human, animal, and environmental sources shared genes associated with AMR. The most prevalent ESBL gene was blaCTX-M, followed by blaTEM and blaSHV. Other ARGs were detected, with prevalence ranging from 3.9% to 16.4%. Horizontal gene transfer, which allows the dissemination of ARGs between genetically diverse bacteria, can occur, necessitating a multidisciplinary approach to address AMR in Ghana.
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