Phage isolation, characterization, and antibiotic resistance profiling in Avian pathogenic Escherichia coli: Integrating data for a possible novel AMR surveillance model

Colibacillosis, caused by Avian Pathogenic Escherichia coli (APEC), poses a significant risk to poultry farming. Antimicrobial resistance (AMR) in APEC isolates is increasing, making management difficult. This study examined antibiotic resistance profiles, antibiotic resistance gene (ARG) presence, and phage susceptibility in 130 APEC isolates. The highest resistance was found against tetracycline and nalidixic acid. PhEcoAP90, an antibiotic alternative, showed instability at high temperatures and extreme pH values. The research suggests a unique AMR surveillance system.