Antibiotic resistance and viral co-infection in children diagnosed with pneumonia caused by Mycoplasma pneumoniae admitted to Russian hospitals during October 2023—February 2024

Mycoplasma pneumoniae (MP) is a common respiratory infection that causes pneumonia, particularly in children. A study aimed to estimate the impact of viral infections on co-infection spectrum in hospitalized children with MPP, determine differences in resistance mutation rates for samples from European and Far East hospitals in Russia, and describe genomic characteristics of MP from Russian patients during MPP outbreaks in 2023-2024. Results showed that 62% of patients with MPP had a viral co-infection, with HPIV and SARS-CoV-2 predominating at 47% and 12.4%, respectively. The 2063 A/G mutation of the 23S gene was found in 40.8% of patients from European Russia and 35.7% of patients from the Far East.