Seasonal Trends and Antibiotic Resistance Profiles of Bacterial Pathogens in Indian Clinical Isolates

This study examines seasonal trends in bacterial infections in an Indian tertiary care setting. It analyzed 1,562 patient samples and found that infections peak in April and March, with Staphylococcus aureus being the most common pathogen. Seasonal trends showed infections peak in summer, while P. aeruginosa and E. faecalis peak in winter. Temperature correlated positively with S. aureus infection, but negatively with P. aeruginosa and E. faecalis. The study highlights the threat of multidrug resistance, especially in Gram-negative bacteria, and emphasizes the need for enhanced infection control and targeted antibiotic stewardship.