Genomic epidemiology reveals geographical clustering of multidrug-resistant Escherichia coli ST131 associated with bacteraemia in Wales

  15 February 2024

This study examines third-generation cephalosporin resistance in bloodstream infections caused by Escherichia coli ST131. 142 genomes were studied in Wales, with clade C/H30 predominant. Welsh strains contain β-lactamase genes, conferring resistance to cephalosporins. The study highlights the value of genomic epidemiology in detecting genetically similar strains in local areas, enabling targeted public health interventions.

Further reading: Nature Communications
Author(s): Rhys T. White et al
Effective Surveillance  
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